American scientists showed that disabling the gene that encodes the enzyme phosphatidic acid phosphatase, increases the risk of developing not only obesity, but also cancer and diabetes. A study published in the Journal of Biological Chemistry, reports Rutgers University (USA).
As a model organism experts were used in the experiments Baker’s yeast. Remove from fungi encoding gene phosphatase phosphatidic acid, leads to accumulation of phosphatidic acid, resulting in cells produced more membrane lipids than is necessary. The findings obtained in experiments with yeast, just and for the people.
“Excess production of membranes allows cells to grow uncontrollably, which is a symptom of a disease resembling cancer,” said co-author Gil-soo Han.
Currently, experts are trying to understand the structure and function of the phosphatidic acid phosphatase, and also learn to control her production. One of the simplest ways that experts call a balanced diet.
Previously, scientists knew that disabling the gene encoding the phosphatidic acid phosphatase, leading to increased risk of obesity. Enzyme opened 1957 in 2006 it was found encoding gene.