BSMU scientists: great chances of surviving on mechanical ventilation in patients without cancer and heart disease
Russian scientists from the Bashkir State Medical University (BSMU) identified three factors that make it possible to predict the chances of death or recovery for patients with coronavirus infection connected to mechanical ventilation devices (ventilators). Izvestia writes about this.
The study involved 200 patients with severe COVID-19, who were in intensive care units of city clinical hospitals in Ufa. They were divided into two groups: one required a connection to a ventilator, the other could breathe on their own.
As a result, factors such as the score on a scale for determining the degree of multiple organ failure (SOFA), the ratio of the number of neutrophils to lymphocytes (indicating a focus of inflammation) and the number of proinflammatory cytokines (indicating a cytokine storm) turned out to be particularly important. If all these indicators are high, the prognosis is less favorable.
The negative indicators are the presence of cancer, as well as complications from the cardiovascular and endocrine systems. Also, the length of time of concomitant diseases and the degree of their compensation played an important role.
“The deceased patients were more often men and initially had statistically significantly higher scores on the SOFA scale, the values of the ratio of the number of neutrophils to lymphocytes and the content of inflammatory markers interleukin-6 (IL-6) in the blood,” said the deputy chief physician for surgical care of the BSMU clinic Ildar Galimov.
It is specified that the SOFA scores are based on the assessment of dysfunction of the main body systems: respiratory, coagulation, hepatic, cardiovascular, neurological, renal. The higher the indicator, the worse the patient's condition.
Earlier, the doctor and TV presenter Alexander Myasnikov named the reasons why people vaccinated against COVID-19 end up in intensive care. According to him, if a younger person gets to the intensive care unit, then most likely the cause was not viral pneumonia. He added that with pneumonia caused by a new coronavirus infection, it can be very difficult to remove a person from mechanical ventilation and the mortality rate among such patients is close to 90 percent.