An important protein for infecting cells with coronavirus has been identified

Swedish scientists have determined how coronavirus interacts with human cell proteins CoV-2 takes control of human cells and uses them to replicate itself. The results of the study, published in the journal Nature Communications, will help develop new drugs for the treatment of COVID-19. To infect cells, viruses use peptide motifs that interact with proteins of the cell itself. Motives in this case are relatively short sequences of amino acids that are conserved during evolution. This is due to the fact that mutations in them lead to the inability of the motive to perform an important function, for example, to bind to certain regions of proteins with which the virus must interact. Scientists were able to determine 269 interactions between coronavirus peptides and cell proteins, including specific interaction between the human G3BP1/2 protein and the ΦxFG peptide motif in the SARS-CoV-2 nucleocapsid (N) protein. The connection between G3BP1/2 and ΦxFG

An important protein for infecting cells with coronavirus has been identified

Swedish scientists have determined how coronavirus interacts with human cell proteins CoV-2 takes control of human cells and uses them to replicate itself. The results of the study, published in the journal Nature Communications, will help develop new drugs for the treatment of COVID-19. To infect cells, viruses use peptide motifs that interact with proteins of the cell itself. Motives in this case are relatively short sequences of amino acids that are conserved during evolution. This is due to the fact that mutations in them lead to the inability of the motive to perform an important function, for example, to bind to certain regions of proteins with which the virus must interact. Scientists were able to determine 269 interactions between coronavirus peptides and cell proteins, including specific interaction between the human G3BP1/2 protein and the ΦxFG peptide motif in the SARS-CoV-2 nucleocapsid (N) protein. The connection between G3BP1/2 and ΦxFG

Weather anomalies were predicted for a number of Russian regions

Forecaster Vilfand: anomalous heat will come to the south and center of European Russia at the end of November part of European Russia at the end of November expects a temperature of five degrees above normal, RIA Novosti reports. According to the forecaster, heat will come to the center of European Russia on November 25: the temperature on that day will be three degrees above normal, and by the weekend – by five degrees. On Sunday, Vilfand predicted up to plus four degrees and a warm southwest wind. “According to calculations, the temperature will even be up to plus five degrees,” he concluded. Vilfand also predicted weather anomalies in a number of other Russian regions. In particular, in the north of European Russia, abnormal cold and “severe frosts” are expected: on November 25 at night it is predicted up to minus ten degrees, and by the end of the week

Weather anomalies were predicted for a number of Russian regions

Forecaster Vilfand: anomalous heat will come to the south and center of European Russia at the end of November part of European Russia at the end of November expects a temperature of five degrees above normal, RIA Novosti reports. According to the forecaster, heat will come to the center of European Russia on November 25: the temperature on that day will be three degrees above normal, and by the weekend – by five degrees. On Sunday, Vilfand predicted up to plus four degrees and a warm southwest wind. “According to calculations, the temperature will even be up to plus five degrees,” he concluded. Vilfand also predicted weather anomalies in a number of other Russian regions. In particular, in the north of European Russia, abnormal cold and “severe frosts” are expected: on November 25 at night it is predicted up to minus ten degrees, and by the end of the week

The place of Russia in the policy of the new German government has been named

Political scientist Kamkin: the new Cabinet of Ministers of Germany will choose a pragmatic approach towards Russia The new government of Germany will take a pragmatic approach towards Russia, therefore is not expected, but the main place in his German foreign policy will be given to relations with the United States. Alexander Kamkin, a leading researcher at the Center for German Studies at the Institute of Europe of the Russian Academy of Sciences, said this in an interview with Lenta.ru. Related materials00: 02 – September 28 Deficit of democracy. Power is changing in Germany. Who will lead the country into the future and what will it be like? 00:01 – September 26 “Merkel leaves bedlam behind” Pro-Russian nationalists are joining the Bundestag. How will Germany change after the elections? According to the expert, the future German Chancellor and the head of the Social Democratic Party (SPD) Olaf Scholz is a

The place of Russia in the policy of the new German government has been named

Political scientist Kamkin: the new Cabinet of Ministers of Germany will choose a pragmatic approach towards Russia The new government of Germany will choose a pragmatic approach towards Russia is not foreseen, but the main place in his German foreign policy will be given to relations with the United States. Alexander Kamkin, a leading researcher at the Center for German Studies at the Institute of Europe of the Russian Academy of Sciences, said this in an interview with Lenta.ru. Related materials00: 02 – September 28 Deficit of democracy. Power is changing in Germany. Who will lead the country into the future and what will it be like? 00:01 – September 26 “Merkel leaves bedlam behind” Pro-Russian nationalists are joining the Bundestag. How will Germany change after the elections? According to the expert, the future German Chancellor and the head of the Social Democratic Party (SPD) Olaf Scholz is a supporter

Russian wine preferences revealed

AKORT: most Russians prefer semi-dry or dry wines, the most popular are red wines Russians' preferences in wine. According to him, the majority of consumers prefer semi-dry or dry wines, red ones are especially popular, RIA Novosti reports. “On average, 40 percent of buyers prefer semi-dry wines, 35 percent prefer dry ones. At the same time, it is precisely the sweetness that remains one of the key criteria when choosing a wine in a store. Over the past two years, the consumption of sweet wines has decreased by an average of 12 percent, “the expert noted. According to Karavaev, the demand for white wines has begun to grow. Two years ago, the ratio of consumption of red and white wines was 70 to 30 percent, today 65 percent prefer red wine, 35 – white and 5 percent sparkling wine. The chairman of the AKORT Presidium predicted growth in the Russian

Russian wine preferences revealed

AKORT: the majority of Russians prefer semi-dry or dry wines, the most popular are red wines Russians' preferences in wine. According to him, the majority of consumers prefer semi-dry or dry wines, red ones are especially popular, RIA Novosti reports. “On average, 40 percent of buyers prefer semi-dry wines, 35 percent prefer dry ones. At the same time, it is precisely the sweetness that remains one of the key criteria when choosing a wine in a store. Over the past two years, the consumption of sweet wines has decreased by an average of 12 percent, “the expert noted. According to Karavaev, the demand for white wines has begun to grow. Two years ago, the ratio of consumption of red and white wines was 70 to 30 percent, today 65 percent prefer red wine, 35 – white and 5 percent sparkling wine. The chairman of the AKORT Presidium predicted growth in

Russian scammers intensify ahead of Black Friday

Marketer Podgorny: the share of phishing emails during the Black Friday period grows sharply The share of phishing emails during the Black Friday sales period “Grows sharply from an average 3-5 percent to 20-30 percent. Kirill Podgorny, Director of Marketing at ESET in Russia and the CIS, told RIA Novosti. According to him, in the week before and a week after the sales, scammers and fake websites are sharply activated all over the world, and the share of phishing e- letters take off. The specialist advised Russian users to check the router settings before making online purchases, download the latest updates for the browser, Android Pay and Apple Pay payment instruments and set a limit on spending on a bank card. “Better get a separate card for online shopping, such as virtual “, – said the marketer, noting that its activation takes only a few minutes. Earlier, an analyst on

Russian scammers intensify ahead of Black Friday

Marketer Podgorny: the share of phishing emails during the Black Friday period grows sharply The share of phishing emails during the Black Friday sales period “Grows sharply from an average 3-5 percent to 20-30 percent. Kirill Podgorny, Director of Marketing at ESET in Russia and the CIS, told RIA Novosti. According to him, in the week before and a week after the sales, scammers and fake websites are sharply activated all over the world, and the share of phishing e- letters take off. The specialist advised Russian users to check the router settings before making online purchases, download the latest updates for the browser, Android Pay and Apple Pay payment instruments and set a limit on spending on a bank card. “Better get a separate card for online shopping, such as virtual “, – said the marketer, noting that its activation takes only a few minutes. Earlier, an analyst on